Apoptosis Reagents and Kits
Abcam Human BSG (CD147) knockout HEK-293T cell lysate.
Human BSG (CD147) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Annexin V-Cy5/DAPI Apoptosis Kit 20assays
Annexin V is a Ca2 -dependent phospholipid-binding protein that specifically binds to phosphatidylserine (PS) Normally PS is localized on the inner leaflet of the cell membrane lipid bilayer During the early stages of apoptosis PS translocates from the inner leaflet to the outer surface of the cell membrane exposing it to the extracellular environment Due to Annexin V s high affinity for PS fluorescently labeled Annexin V (Cy5) can be used as a fluorescent probe to detect apoptotic cells through flow cytometry or fluorescence microscopy with staining taking only 10-20 minutes DAPI specifically binds to double-stranded DNA emitting blue fluorescence but normally cannot permeate intact cell membranes However DAPI can enter late-stage apoptotic or dead cells and stain their nuclei Simultaneous staining with Annexin V-Cy5 and DAPI allows differentiation of cells at various stages of apoptosis and cell death
Abcam Human IRS2 knockout HEK-293 cell lysate.
Human IRS2 knockout HEK-293 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Z-FF-FMK, Purity: ≥95%, CAS: 105608-85-3, 50 mg
An inhibitor of cathepsin B (Ki = 2.7 nM); inhibits cell division, cell cycle progression, DNA replication, and chromosome decondensation in isolated T. niger fertilized embryos at 100 µM; prevents Aβ40-induced increases in cathepsin L activity, as well as prevents Aβ40-induced apoptosis, DNA fragmentation, and increases in cleaved PARP levels, in primary rat cortical neurons at 10 µM; inhibits quinolinic acid-induced nuclear translocation of NF-κB, as well as inhibits quinolinic acid-induced increases in phosphorylated IκBα and IKKα levels, in the unilateral striatum in rats at 5 nmol/animal
Abcam Human PRKCD (PKC delta) knockout HeLa cell lysate.
Human PRKCD (PKC delta) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx KILR MOLT-4 (Human) Cytotoxicity Assay Kit (cell pool)
The KILR MOLT-4 (Human) Stable Cell Pool Cytotoxicity Assay utilizes the engineered stable target cell pool that is used to measure direct death mediated by immuno-oncology treatments via ADCC, CDC, and ADCP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Abcam Human AES (Amino-terminal enhancer of split) knockout HCT116 cell lysate.
Human AES (Amino-terminal enhancer of split) knockout HCT116 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PFN2 (Profilin 2) knockout HeLa cell lysate.
Human PFN2 (Profilin 2) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human CEBPB (CEBP Beta) knockout HeLa cell lysate.
Human CEBPB (CEBP Beta) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Annexin A5/ANXA5 protein, mouse (His, Myc) | >95.0% | 100UG
Recombinant mouse Annexin A5 (ANXA5) is a His- and Myc-tagged protein supplied as a lyophilized powder for biochemical and cell biology applications. It binds negatively charged phospholipids in a calcium-dependent manner and is commonly used to detect apoptosis, study membrane binding, and promote vesicle aggregation.
- His- and Myc-tagged recombinant protein for easy detection and purification.
- Produced in Escherichia coli and supplied as lyophilized powder for stability.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Formulated with Tris-HCl, NaCl, and trehalose to preserve activity on drying.
- Useful for apoptosis assays, phospholipid binding studies, and membrane fusion experiments.
- Store at -20°C; after reconstitution store at 4°C short term or freeze aliquots for long-term storage.
- Not recommended to reconstitute below 100 μg/mL in ddH2O to maintain integrity.
Enzo Life Sciences Apoptosis Activator 2 (5mg). CAS: 79183-19-0
Induces apoptosis by promoting the oligomerization of Apaf-1 into the mature, functional apoptosome, triggering caspase-9 activation resulting in activated caspase-3. Shows strong selectivity for cancer cells against normal cell lines. Acts in a similar way like apoptosis inducer PETCM (ALX-420-031). Alternative name: 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione. Purity: ≥98% (HPLC). Appearance: Orange to red solid. Solubility: Soluble in DMSO (5mg/ml), methanol (5mg/ml) or 100% ethanol. Long Term Storage: +4°C.
Abcam Human MTHFD2 knockout HEK-293T cell lysate.
Human MTHFD2 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PRDX1 (Peroxiredoxin 1/PAG) knockout HEK-293T cell lysate.
Human PRDX1 (Peroxiredoxin 1/PAG) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement